1.Identification
1.1 GHS Product identifier
Product name | monolinuron |
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1.2 Other means of identification
Product number | - |
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Other names | N’-(4-chlorophenyl)-N-methoxy-N-methylurea |
1.3 Recommended use of the chemical and restrictions on use
Identified uses | For industry use only. |
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Uses advised against | no data available |
1.4 Supplier's details
1.5 Emergency phone number
Emergency phone number | - |
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Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
Specific target organ toxicity – repeated exposure, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
2.2 GHS label elements, including precautionary statements
Pictogram(s) | ![]() ![]() ![]() |
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Signal word | Warning |
Hazard statement(s) | H302 Harmful if swallowed H373 May cause damage to organs through prolonged or repeated exposure H410 Very toxic to aquatic life with long lasting effects |
Precautionary statement(s) | |
Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment. |
Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P314 Get medical advice/attention if you feel unwell. P391 Collect spillage. |
Storage | none |
Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
---|---|---|---|---|
monolinuron | monolinuron | 1746-81-2 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest.
In case of skin contact
Rinse skin with plenty of water or shower.
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Rest. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
no data available
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Treatment should include decontamination and aggressive supportive care. Additionally, methylene blue, 1 to 2 mg/kg/dose, should be given if significant methemoglobinemia is present. /Urea-substituted herbicides/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, powder, foam, carbon dioxide.
5.2 Specific hazards arising from the chemical
no data available
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Do NOT wash away into sewer. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
Physical state | COLOURLESS CRYSTALS. |
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Colour | COLORLESS CRYSTALS |
Odour | ODORLESS |
Melting point/ freezing point | 76-78oC |
Boiling point or initial boiling point and boiling range | no data available |
Flammability | Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. |
Lower and upper explosion limit / flammability limit | no data available |
Flash point | 100?°C |
Auto-ignition temperature | no data available |
Decomposition temperature | no data available |
pH | no data available |
Kinematic viscosity | no data available |
Solubility | 735 ppm in water at 20°C; sol in alcohol, acetone, benzene, toluene |
Partition coefficient n-octanol/water (log value) | log Kow = 2.30 |
Vapour pressure | 1.5X10-4 MM HG AT 22 DEG C |
Density and/or relative density | 1.304g/cm3 |
Relative vapour density | no data available |
Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
STABLE AT MELTING POINT & IN SOLN BUT SLOWLY DECOMPOSES IN ACIDS & BASES...
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
no data available
10.6 Hazardous decomposition products
no data available
11.Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
Biodegradation of monolinuron in activated sludge resulted in a 0.9% loss of the initial concentration after 5 days(1). Monolinuron, dissolved in acetone/water and sprayed onto ground waste (compost), was demethylated in small amounts (0.4% of the extracted radioactivity) after 3 weeks to N-methoxy-N'-4-chlorophenyl-urea, whereas 86.2% of the extractable radioactivity was unaffected started material(2). A mixed bacterial culture (containing Gram-negative aerobic rods and Gram-positive aerobic non-spore-forming rods, and cocco-bacilli) from soil (sandy loam) was able to degrade monolinuron completely after 10 days(3).
12.3 Bioaccumulative potential
Bioaccumulation tests using activated sludge, algae, and fish (golden ide) gave BCF values for monolinuron of 70 (5-day), 40 (1-day), and 20 (3-day), respectively(1). The BCF for monolinuron has been estimated to be 17 and 10 based on water solubility and Koc, respectively(2). Another BCF value monolinuron was calculated to be 22(3). The experimental BCF value of monolinuron in the algae Chloroella was 33 after exposure to 50 ug/l for 24 hours(4). The BCF value for monolinuron in fish (golden orfe) and algae (Chlorella Fusca) were experimentally determined to be <20 (3-day at 45 ug/l) and 60 and 140 (24 hours at 50 ug/l), respectively(5). According to a recommended classification scheme(6), the experimental BCF values suggest that monolinuron should undergo moderate to high bioconcentration in aquatic organisms(SRC).
12.4 Mobility in soil
The Koc for monolinuron has been estimated and experimentally determined to be 200(1,4). The Koc for monolinuron has also been experimentally determined to be 69.2(2). An average Koc value has been reported to be 40 in soils with organic carbon contents ranging from 0.58-2.3%(3). The Koc for monolinuron has been determined to be 60.3(5). The Koc values determined for monolinuron ranged from 211 to 2025 with an average of 517 in eight Czechoslovakian soils with organic matter contents ranging from 0.1-4.6%(6). The average Koc value for monolinuron in 10 different soils was determined to be 271.5(7). Another average Koc value has been determined to be 60(8). According to a recommended classification scheme(9), these Koc values suggest that monolinuron should have slight to very high mobility in soil(SRC).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
ADR/RID: UN3077 | IMDG: UN3077 | IATA: UN3077 |
14.2 UN Proper Shipping Name
ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. |
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. |
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. |
14.3 Transport hazard class(es)
ADR/RID: 9 | IMDG: 9 | IATA: 9 |
14.4 Packing group, if applicable
ADR/RID: III | IMDG: III | IATA: III |
14.5 Environmental hazards
ADR/RID: yes | IMDG: yes | IATA: yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
Chemical name | Common names and synonyms | CAS number | EC number |
---|---|---|---|
monolinuron | monolinuron | 1746-81-2 | none |
European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
EC Inventory | Listed. | ||
United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
New Zealand Inventory of Chemicals (NZIoC) | Not Listed. | ||
Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Not Listed. | ||
Vietnam National Chemical Inventory | Not Listed. | ||
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Not Listed. |
16.Other information
Information on revision
Creation Date | Aug 19, 2017 |
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Revision Date | Aug 19, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/