托吡酯
CAS: 97240-79-4
托吡酯的化学名称为2,3:4,5-双-0-(1-甲基亚乙基）-β-D吡喃果糖氨基磺酸酯，分子式为C12 H21 NO8S，分子量为339.36。托吡酯为白色晶体粉末，有苦味，极易溶于氢氧化钠或磷酸钠等pH值为9-10的碱性溶液中，易溶于丙酮，氯仿，二甲亚砜和乙醇。在水中的溶解度为9.8 mg/mL，其饱和溶液的pH值为6.3。 本药为带有压纹的圆形包衣片，有下述不同的规格和颜色 :25 mg :白色，一面刻有"TOP"，另一面刻有"25"。50 mg :淡黄色，一面刻有"TOP"，另一面刻有"50"。100 mg :黄色，一面刻有"TOP"，另一面刻有"100"。
也叫妥泰，属抗癫痫药，为广谱抗癫痫新药，对各类癫痫发作均有效，其中原发性利继发性全身强直一阵挛发作及单纯或复杂部分发作效果尤其明显。对肌阵挛、婴儿痉挛也有效。作为心境稳定剂用于治疗双相障碍。
Topiramate
CAS: 97240-79-4
Topiramate chemical name is 2,3:4,5- -0- ( 1- methyl and ethyl ) -β -D glucopyranosyl fructose amino sulfonic acid ester, molecular formula is C12 H21 NO8S, the molecular weight is 339.36. Topiramate is a white crystalline powder, bitter, very soluble in sodium hydroxide or sodium phosphate and pH value for the 9-10 alkaline solution, soluble in acetone, chloroform, two dimethyl sulfoxide and ethanol. Solubility in water of 9.8 mg/mL, the saturated solution pH value of 6.3. This medicine is embossed circular coated tablets, the different specifications and colors: white :25 mg, one side of which is engraved with " TOP ", the other side is carved with " 25 ". 50 mg: pale yellow, one side of which is engraved with " TOP ", the other side is carved with " 50 ". 100 mg: yellow, one side of which is engraved with " TOP ", the other side is carved with " 100 ".Also called topiramate, belongs to anticonvulsants, broad-spectrum antiepileptic drug, for all types of epileptic seizures are valid, in which the primary and secondary generalized tonic-clonic seizures and simple or complex partial seizure effects particularly evident. On myoclonus, infantile spasms is also effective. As a mood stabilizer used in the treatment of bipolar disorder
