基本信息
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人胰高血糖素样肽-1
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106612-94-6
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7-37-Glucagon-like peptide I (human); Insulinotropin (human); Peptide GLP-1 (human glucose-lowering peptide-1)
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C151H228N40O47
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3355.67
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7-37-Glucagon-likepeptide I (human)
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1.48±0.1 g/cm3(Predicted)
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Glucagon-relatedpeptide 1 (Rana catesbeiana), 3-L-glutamicacid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-31-glycine-32-de-L-lysine-;10: PN: US20080299096 SEQID: 9 unclaimed sequence; 10: PN: WO03103572 SEQID: 16unclaimed protein; 10: PN: WO2008150821 SEQID: 9 unclaimed protein; 111: PN:WO0198331 TABLE: 1 claimed protein; 116: PN: WO2007124463 SEQID: 1 claimedsequence; 11: PN: EP1972349 SEQID: 1 unclaimed sequence; 11: PN: US6284725SEQID: 3 unclaimed protein; 11: PN: WO0066138 PAGE: 11 unclaimed protein; 11:PN: WO0136643 FIGURE: 4 unclaimed protein; 11: PN: WO2008101017 SEQID: 50unclaimed sequence; 137: PN: WO2006074600 SEQID: 2 unclaimed sequence; 13: PN:WO2004056313 SEQID: 11 unclaimed sequence; 14: PN: WO2005097175 SEQID: 15claimed protein; 15: PN: WO2007076319 SEQID: 15 claimed protein; 15: PN:WO2007081302 SEQID: 15 claimed sequence; 17: PN: WO0039278 SEQID: 23 unclaimedprotein; 18: PN: WO2004022004 SEQID: 2 claimed sequence; 18: PN: WO2007062531SEQID: 18 unclaimed sequence; 19: PN: WO02072605 SEQID: 19 unclaimed protein;1: PN: CN101463081 SEQID: 1 claimed protein; 1: PN: CN1982336 SEQID: 1unclaimed sequence; 1: PN: US20040143104 SEQID: 21 unclaimed sequence; 1: PN:US20060286129 SEQID: 1 claimed sequence; 1: PN: WO0155213 SEQID: 1 claimedprotein; 1: PN: WO03014318 SEQID: 21 claimed protein; 1: PN: WO2004093823SEQID: 1 claimed protein; 1: PN: WO2005019262 SEQID: 1 claimed protein; 1: PN:WO2005027978 SEQID: 1 unclaimed protein; 1: PN: WO2005028516 SEQID: 1 claimedprotein; 1: PN: WO2006126673 SEQID: 1 claimed protein; 1: PN: WO2007049695SEQID: 2 claimed sequence; 1: PN: WO2008097504 PAGE: 42 unclaimed sequence; 1:PN: WO2008132477 PAGE: 5 unclaimed sequence; 1: PN: WO2009020802 SEQID: 3unclaimed sequence; 1: PN: WO2009035540 SEQID: 3 unclaimed sequence; 1: PN:WO2009067268 PAGE: 9 unclaimed sequence; 1: PN: WO2009080032 SEQID: 1 unclaimedsequence; 1: PN: WO2009083549 SEQID: 1 unclaimed sequence;
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详细信息
中文名称：人胰高血糖素样肽-1
英文名称：Human GLP-1 (7-37)
别名：醋酸人胰高血糖素样肽-1 人胰高血糖素样肽-1(7-37)
CAS号：106612-94-6
分子式：C151H228N40O47
分子量：3355.67
保存:干燥低温-20度~-80度
包装:5mg, 10mg, 50mg, 1G, 10G, 100G, 或更大包装
序列:H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
南京莱昂生物专业大量提供优质美容肽类产品, 及提供多肽合成定制服务
公司简介
南京莱昂生物科技有限公司以提供线性多肽和各种修饰性多肽的定制合成服务为主。如2-140aa线性多肽，磷酸化多肽（Phospho-peptide）、磺酸化多肽，生物素标记肽、各种荧光（FITC、FAM 、罗丹明等）标记肽、环肽(Cyclic-peptide)、甲基化多肽(Methyl-peptide)，糖肽，巯基上修饰多肽等。公司还致力于小分子定制合成、基因合成、生物可降解聚合物等生物类产品。公司建立起高效、稳定、高通量的生物化学产品合成平台，为客户提供稳定、高效、诚信的服务。我们相信莱昂生物科技优质的服务、的技术、高质量的产品、具竞争力的价格是您可靠选择。
1、 普通线性多肽:链长至150个氨基酸，毫克至公斤级，纯度可达99%。1-10aa多肽，一般1周即可完成。11-40aa多肽一般2周即可完成。40-70aa多肽3周即可完成。（如客户特需加急产品还可以周期更短）。源于公司严格的管理和高效的合成团队，我们粗品一次正确率可达到 98%以上。
2、 修饰类：
1）N端修饰 ：
N端氨基封闭修饰：{Ac},Acetylation，{Br-Ac},Bromoacetyl, {CBZ},Benzyloxycarbonyl {Boc},tertbutoxycarbonyl, {Suc},succiny {Acryl}, acryl, {For}, Formylation {pGlu},{Pyr}, Pyroglutamyl {Mpa},3-Mercaptopropy{Mal},Maleimide,Maleoyl-b-Ala，{Glucose-}葡萄糖。
聚乙二醇类修饰：minPEG~PEG5000
螯合物类修饰：NOTA DOTA DTPA HYNIC
脂肪酸类修饰：{But}, Butyric acid C4 {Iba}, isobutyric acid C4 {Hex}, Hexanoic acid C6 6-heptenoic acid C6 {Oct}, Octanoic acid C8, {F-Oct}, Perfluoro Octanoic acid F15C8, {Dec}, Decanoic acid C10 , {F-Dec}, Perfluoro Decanoic acid F19C10, {Lau}, Lauric acid C12 , {F-Lau}, Perfluoro Lauric acid F23C12, {Myr}, Myristic acid C14 , {F-Myr}, Perfluoro Myristic acid F27C14 , {Pal}, Palmitic acid C16, {Ste}, Stearic acid C18
等其他修饰。
2）C端类修饰：
{NH2}, Amidation, {-CHO}, {-ol}, {Cya}, Cysteamide {pNA},p-nitroaniline {AMC}, 7-Amino-4-methylcoumarin {AFC} -OMe (C-terminal) -OEt (C-terminal) -OBzl (C-terminal)- OtBu (C-terminal) -NHMe (C-terminal) -NHEt (C-terminal) -TBzl (C-terminal) -NHNH2 (C-terminal) -ED (C-terminal), -NH-CH2CH2-NH2 Azagly Abz 等其他修饰。
3）荧光修饰类：
FITC (N-Terminal)
EDFITC (C temrinus)
Lys(FITC) (middle)
Lys(FITC) (C temrinus)
Lys(FITC) (N terminus)
FITC-LC (N-Terminal)
5-FAM (N-Terminal)
6-FAM (N-Terminal)
ED5-FAM (C temrinus)
Lys(5-FAM) (middle)
Lys(5,6-FAM)
Lys(5-FAM) (C temrinus)
Lys(5-FAM) (N-Terminus)
5-FAM-LC (N-Terminal)
Dansyl (N-Terminal)
EDDansyl (C temrinus)
Lys(Dansyl) (middle)
Lys(Dansyl) (C temrinus)
Lys(Dansyl) (N-Terminus)
Dansyl-LC (N-Terminal)
TAMRA (N-Terminal)
5(6)-TAMTA-
EDTAMRA (C temrinus)
Lys(TAMRA) (middle)
Lys(TAMRA) (C temrinus)
Lys(TAMRA) (N-terminus)
TAMRA-LC (N-Terminal)
Lys(Dnp) (middle)
D-Lys(Dnp) (middle)
Dab(Dnp) (middle)
Dap(Dnp) (middle)
EDDnp (C terminus)
MCA (N-Terminal)
Lys(MCA) (middle)
Lys(MCA) (C temrinus)
Lys(MCA) (N-terminus)
Rhodamine B- (N-Terminal)
Lys(Rhodamine B)
Cy3- (N-Terminal)
等其他荧光修饰
4）非常规氨基酸修饰：
{D-Allo-Ile} {Gamma-Glu} {D-Gamma-Glu} {Cys(Cam)} {Cys(Acm)} {Lys(Ac)} {Lys(Dde)} {Tle} {Ser(octanoic acid)}
{Ser(Lipoic acid)} {Hyp} {Phg} {D-Phg} {Nva} {D-Nva} {Nle} {D-Nle} {Cit} {D-Cit} {Orn} {D-Orn} {Pen} {D-Pen} {Cha}
{D-Cha} {Chg} {D-Chg} {Oic} {Tic} DMT
Lys(Biotin) (middle) Lys(Biotin) (C temrinus) Lys(LC-Biotin) (middle) Lys(LC-Biotin) (C terminus) Lys(Biotin) (N terminus) Abz Tyr (3-NO2) Glu(EDANS)-NH2 DABCYL Lys(DABCYL) Lys(Abz) {pSer} {pTyr} {pThr}
等其他非常规氨基酸。
5)偶联修饰：
BSA-Peptide N terminus
BSA-Peptide C terminus
BSA-Peptide Cys
KLH-Peptide N terminus
KLH-Peptide C terminus
KLH-Peptide Cys
OVA-Peptide N terminus
OVA-Peptide C terminus
OVA-Peptide Cys
6）二硫键以及酰胺环类修饰：
Mono Disulfide bridge
Double Disulfide bridge
Triple Disulfide bridge
Random Triple Disulfide bridge
Same Seq. Inter-Disulfide bridge
Different Inter-Disulfide bridge
Amide cyclic (end)
Amide cyclic (Side chain)
Orn side chain Amide cyclic
以上仅为部分修饰
