C46H65N15O12S2
Quick Details
|
Product Name |
Argipressin |
|
CAS |
113-79-1 |
|
EINECS |
204-035-4 |
|
Molecular Formula |
C46H65N15O12S2 |
|
Molecular Weight |
1084.23 |
|
Appearance |
White powder |
|
Application |
Used in the treatment of vasodilatory shock, cardiopulmonary resuscitation, diabetes insipidity hemorrhagic disease. |
|
Purity |
98% |
|
storage |
seal |
Description
Arginine vasopressin (AVP), also known as vasopressin, is an important neurotransmitter in the central nervous system. It is a 9-peptide hormone secreted by AVP neurons of the hypothalamus suprachiasmatic nucleus (SON) paravp nucleus (PVN). It is closely related to body fluid metabolism, blood volume, cardiovascular function, body temperature balance, learning memory, adrenal cortical hormone secretion. It plays an important physiological role in water resorption, vasoconstriction, secretion memory of adrenal cortical hormone (ACTH), has the functions of elevating blood pressure, resisting diuresis, participating in memory, limiting fever promoting deheating. At the same time, it also has a wide range of cardiovascular effects, such as regulating sodium water retention vascular contraction, directly regulating cardiac cells, participating in cardiac hypertrophy, myocardial fibrosis, arrhythmia other effects. It has been successfully used in the treatment of vasodilatory shock, cardiopulmonary resuscitation, diabetes insipidity hemorrhagic disease.
Adverse reactions of AVP are rare, mainly including skin necrosis severe limb ischemia. Some patients may have changes in liver function coagulation function, the incidence of hyponatremia is very rare, which often occurs in patients with high dosage.
