Acetyl Hexapeptide-8
Argireline
Key Features
Siped®AH-8 is a solution of acetyl hexapeptide-8. Siped®AH-8 reduces the depth of the wrinkles caused by the contraction of the muscles of facial expression, especially in the forehead around the eyes. Siped®AH-8 is a safer, cheaper, milder alternative to Botulinum Toxin.
INCI P Glycerin - Water (Aqua) - Butylene Glycol - Acetyl Hexapeptide-8
CAS 616204-22-9
Sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
Properties
Siped®AH-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 fa position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle cannot dock release neurotransmitters efficiently therefore muscle contraction is attenuated, preventing the formation of lines wrinkles.
Formulation Tips
1 incorporated in cosmetic formulations at room temperature.
2 can be compatible with carbomer
