Trolox 奎诺二甲基丙烯酸酯水溶性维生素E 53188-07-1,98%

Trolox 奎诺二甲基丙烯酸酯水溶性维生素E 53188-07-1(53188-07-1)

现现货供应

CAS NO：: 53188-07-1

纯度：: 98%

规格：: 100mg瓶,500mg瓶,1g瓶

价格：: 80.0元 - 500.0元

: 马上询价

基本信息

产品名称：奎诺二甲基丙烯酸酯
CAS NO：53188-07-1
中文别名：(±)-6-羟基-2,5,7,8-四甲基色烷-2-羧酸
分子式：C₁₄H₁₈O₄
分子量：250.29
英文名称：2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-
EINECS：258-422-8
密度：1.219 g/cm³
英文别名：2H-1-Benzopyran-2-carboxylicacid, 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-, (?à)-;(R,S)-6-Hydroxy-2,5,7,8-tetramethyl-2-chromanecarboxylic acid; (?à)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylicacid; (?à)-Trolox;6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; Trolox; Trolox C
闪点：171 °C
熔点：187-189 °C(lit.)
沸点：450.3 °C at 760mmHg
毒性：

详细信息

Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid (sc-204753) p-coumaric acid (sc-215648). Studies show that lipid peroxidation, cytotoxicity, apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aeruginosa microcystin-LR in Artemia franciscana nauplii.

Technical Information

Appearance: White

Physical State: Solid

Solubility: Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly), DMSO (~20 mg/ml), DMF (~20 mg/ml), PBS( pH7.2) (~3 mg/ml).

Storage: Store at -20° C

Melting Point: 187-189 °C (lit.)

Boiling Point: 450.26 °C at 760 mmHg

Density: 1.22 g/cm3

Refractive Index: n20D 1.57

IC50: Rattus norvegicus: EC5050 = 77.8 μM; COX2: IC50 = 150 nM (human); HL-60 (Promyeloblast leukemia cells): IC50 = 3.6 μM (human); Bos taurus: IC50 = 5 μM; COX1: IC50 = 130 nM (human); Rattus norvegicus: IC50 = 14 μM; Brain: IC50 = 41.57 μM (Rattus norvegicus); MCF7 (Breast carcinoma cells): IC50 = 1461 μM (human); Radical scavenging activity: IC50 = 10.6 μM

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