基本信息
-
东莨菪碱氢溴酸盐
-
114-49-8
-
Hyoscine hydrobromide
-
C17H21NO4.BrH
-
384.26
-
Benzeneacetic acid, a-(hydroxymethyl)-, (1a,2b,4b,5a,7b)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobromide (1:1), (aS)-
-
204-050-6
-
-
1aH,5aH-Tropan-3a-ol, 6b,7b-epoxy-, (-)-tropate (ester), hydrobromide (8CI);Benzeneacetic acid, a-(hydroxymethyl)-, (1a,2b,4b,5a,7b)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobromide, (aS)- (9CI); Benzeneacetic acid, a-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobromide, [7(S)-(1a,2b,4b,5a,7b)]-; Scopolamine bromide (6CI);3-Oxa-9-azatricyclo[3.3.1.02,4]nonane, benzeneacetic acid deriv.; (-)-Hyoscinehydrobromide; (-)-Scopolamine bromide; (-)-Scopolamine hydrobromide; Beldavrin;Euscopol; Hydroscine hydrobromide; Hyocine F hydrobromide; Hyoscine bromide;Hyoscine hydrobromide; Hysco; Isoscopil; Kwells; Scopamin; Scopolaminehydrobromide; Scopolaminium bromide; Scopolammonium bromide; Scopos; Sea Legs;Sereen; Triptone; Wellcome Brand Scopolamine hydrobromide Injection; l-Hyoscinehydrobromide; l-Scopolamine hydrobromide
-
232.2 °C
-
195-199°C (dry matter)(lit.)
-
460.3oC at 760 mmHg
-
详细信息
氢溴酸东莨菪碱
英文名:Scopolamine Hydrobromide
分子式和分子量:C17H21NO4.HBr.3H2O 438.32
本品为 6β,7β- 环氧-1αH ,5αH-托烷-3α- 醇(-) 托品酸酯氢溴酸盐三水合物。
按干燥品计算,含C17H21NO4.HBr 不得少于99.0%。
性状:氢溴酸东莨菪碱为无色结晶或白色结晶性粉末;无臭;微有风化性。
氢溴酸东莨菪碱在水中易溶,在乙醇中略溶,在氯仿中极微溶解,在乙醚中不溶。
熔点氢溴酸东莨菪碱的熔点(附录Ⅵ C)为195 ~199 ℃,熔融时同时分解。
比旋度 取氢溴酸东莨菪碱,精密称定,加水溶解并定量稀释制成每1ml 中约含50mg的溶液,
依法测定(附录Ⅵ E),比旋度为-24°至-27°。