Section 1. Chemical Product and Company Identification
Catalog
Dimenhydrinate
Common Name/ DI127
Number(s).
Trade Name
523-87-5
CAS#
Manufacturer
SPECTRUM CHEMICAL MFG. CORP. RTECS XH5082000
TSCA TSCA 8(b) inventory:
Dimenhydrinate
Commercial Name(s) Not available.
CI# Not available.
Synonym 8-Chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione compd.
IN CASE OF EMERGENCY
with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1);
Anautine;
Andramine;
Aviomarin;
Dimenhydrinate;
Diphenhydramine 8-chlorotheophylline;
Diphenhydrinate;
Ethylamine, N,N-dimethyl-2-(diphenylmethoxy)-,
compd. with 8-chlorotheophylline;
Gravinol
Novamin;
Novamine;
Teodramin;
O-Benzhydryldimethylaminoethanol 8-chlorotheophyllinate;
Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline;
2-(Benzhydryloxy)-N,N-dimethylethylamine
compd. with 8-chlorotheophylline;
Chloranautine;
8-Chlorotheophylline, compd.
with 2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1);
Diamarin;
Dramamin;
Dramamine;
Dramarin;
Dramyl;
Dromyl;
Eldodram;
Gravinol (antiemetic);
Gravol;
Menhydrinate;
Neo-navigan;
Permital;
Supremal;
Travelin;
Travelmin;
Vomex A;
Xamamina
Chemical Name Theophylline, 8-chloro-, compd. with
2-(diphenylmethoxy)-N,N-dimethylethylamine (1:1)
Not available. CALL (310) 516-8000
Chemical Family
Dimenhydrinate
Chemical Formula C17H21NO.C7H7ClN4O2
SPECTRUM CHEMICAL MFG. CORP.
Section 2.Composition and Information on Ingredients
Exposure Limits
TWA (mg/m3) STEL (mg/m3) CEIL (mg/m3) % by Weight
Name CAS #
1) Dimenhydrinate 523-87-5 100
Toxicological Data Not applicable.
on Ingredients
Section 3. Hazards Identification
Potential Acute Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
CARCINOGENIC EFFECTS: Not available.
Potential Chronic Health
MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
Effects
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin Contact
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation
develops. Cold water may be used.
Serious Skin Contact Not available.
Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Get medical attention.
Serious Inhalation Not available.
Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
Serious Ingestion Not available.
Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Flammable Limits Not available.
Products of Combustion These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated compounds.
Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of shocks, of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
Dimenhydrinate
Fire Fighting Media SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Special Remarks on Material in powder form, capable of creating a dust explosion.
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential
dust explosion hazard.
Hazards
Section 6. Accidental Release Measures
Small Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
water on the contaminated surface and allow to evacuate through the sanitary system.
Section 7. Handling and Storage
Precautions Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately
and show the container or the label. Keep away from incompatibles such as oxidizing agents.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Storage
Section 8. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal Protection Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
a Large Spill used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
specialist BEFORE handling this product.
Exposure Limits Not available.
Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Crystalline powder.) Odor Odorless.
Taste Not available.
Molecular Weight 469.96 g/mole
Color White.
pH (1% soln/water) Not available.
Not available.
Boiling Point
Melting Point 102-107°C (215.6-224.6°F)
Not available.
Critical Temperature
Specific Gravity Not available.
Vapor Pressure Not applicable.
Vapor Density Not available.
Volatility Not available.
Not available.
Odor Threshold
Water/Oil Dist. Coeff. Not available.
Not available.
Ionicity (in Water)
Dispersion Properties Not available.
Dimenhydrinate
Solubility Soluble in cold water.
Freely soluble in alcohol.
Soluble in chloroform , benzene.
Insoluble in diethyl ether.
Section 10. Stability and Reactivity Data
Stability The product is stable.
Not available.
Instability Temperature
Conditions of Instability Excess heat, dust generation, incompatible materials
Incompatibility with various Reactive with oxidizing agents.
substances
Corrosivity Non-corrosive in presence of glass.
Not available.
Special Remarks on
Reactivity
Special Remarks on Not available.
Corrosivity
Polymerization Will not occur.
Section 11. Toxicological Information
Routes of Entry Inhalation. Ingestion.
Toxicity to Animals Acute oral toxicity (LD50): 1320 mg/kg [Rat].
Chronic Effects on Humans MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast.
Other Toxic Effects on Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Special Remarks on Not available.
Toxicity to Animals
Special Remarks on May affect genetic material (mutagenic)
Chronic Effects on Humans
Special Remarks on other Acute Potential Health Effects:
Toxic Effects on Humans Skin: May cause skin irritation.
Eyes: May cause eye irritation.
Inhalation: May cause respiratory tract irritation.
Ingestion: May be harmul is swallowed. May cause dry mouth, adbominal distress vomiting, nausea,
diarrhea or constipaton, anorexia. May affect behavior (central nervous system (drowsiness, lethargy, fatigue.
excitement, hallucinations; hypnosis, convulsions, coma), cardiovascular system (cardiac arrhythmias).
Section 12. Ecological Information
Ecotoxicity Not available.
BOD5 and COD Not available.
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products
may arise.
Toxicity of the Products The products of degradation are as toxic as the product itself.
of Biodegradation
Special Remarks on the Not available.
Products of Biodegradation
Dimenhydrinate
Section 13. Disposal Considerations
Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental
control regulations.
Section 14. Transport Information
DOT Classification
Not a DOT controlled material (United States).
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
DOT (Pictograms)
Section 15. Other Regulatory Information and Pictograms
California prop. 65: This product contains the following ingredients for which the State of California has found
Federal and State
to cause birth defects which would require a warning under the statute: No products were found.
Regulations
TSCA 8(b) inventory: Dimenhydrinate
California California prop. 65: This product contains the following ingredients for which the State of California has
Proposition 65 found to cause cancer which would require a warning under the statute: No products were found.
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause birth defects which would require a warning under the statute: No products were found.
Other Regulations EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS
No. 208-350-8).
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Not listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Listed on National Inventory (KECI).
Philippines: Listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC) R22- Harmful if swallowed. S46- If swallowed, seek medical advice
immediately and show this container or label.
Health Hazard
HMIS (U.S.A.) 1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
Dimenhydrinate
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
SECTION 16 - ADDITIONAL INFORMATION
N/A
