右旋糖

外观与性状：

白色结晶粉末

密度：

1.544g/cm3

熔点：

150-152 °C(lit.)

沸点：

527.1ºC at 760 mmHg

闪点：

286.7ºC

水溶解性：

Soluble

折射率：

53 ° (C=10, H2O)

存储条件/存储方法：

塑料袋外套编织袋或牛皮纸袋包装。贮存于阴凉干燥处。

稳定性相关：

常温常压下稳定。

其它信息：

1.       性状：为白色颗粒状粉末。无臭，味甜。

海关代码：

2940000000

WGK_Germany：

1
德国有关水污染物质的分类清单

危险类别码：

R36/37/38

安全说明：

S26-S36/37-S24/25

RTECS号：

LZ6600000

安全标志：

S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
:
S24/25:防止皮肤和眼睛接触。
S53:避免暴露——使用前先阅读专门的说明。
S25:避免接触眼睛。

危险标志：

Xi

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LZ6600000

CHEMICAL NAME :

D-Glucose

CAS REGISTRY NUMBER :

50-99-7

BEILSTEIN REFERENCE NO. :

1724615

LAST UPDATED :

199710

DATA ITEMS CITED :

28

MOLECULAR FORMULA :

C6-H12-O6

MOLECULAR WEIGHT :

180.18

WISWESSER LINE NOTATION :

T6OTJ BQ CQ DQ EQ F1Q -D,GLU

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

25800 mg/kg

TOXIC EFFECTS :

Behavioral - coma Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

18 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

9 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

8 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

20 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

12 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

15400 gm/kg/22W-C

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

2 gm/kg

SEX/DURATION :

female 28 week(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

DOSE :

2 gm/kg

SEX/DURATION :

female 39 week(s) after conception

TOXIC EFFECTS :

Reproductive - Maternal Effects - other effects Reproductive - Effects on Embryo or Fetus - other effects to embryo

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

DOSE :

1057 ug/kg

SEX/DURATION :

female 39 week(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - hepatobiliary system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

DOSE :

1300 mg/kg

SEX/DURATION :

female 39 week(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Newborn - biochemical and metabolic Reproductive - Effects on Newborn - behavioral

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

300 gm/kg

SEX/DURATION :

female 30 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

20 gm/kg

SEX/DURATION :

female 6-8 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

DOSE :

20 gm/kg

SEX/DURATION :

female 6-8 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - eye/ear

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Multiple routes

DOSE :

20 gm/kg

SEX/DURATION :

female 6-8 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Multiple routes

DOSE :

20 mg/kg

SEX/DURATION :

female 6-8 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - urogenital system

MUTATION DATA

TYPE OF TEST :

Mutation in mammalian somatic cells

TEST SYSTEM :

Rodent - mouse Lymphocyte

DOSE/DURATION :

179 mmol/L

REFERENCE :

MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81836 No. of Facilities: 16738 (estimated) No. of Industries: 117 No. of Occupations: 90 No. of Employees: 136870 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81836 No. of Facilities: 11017 (estimated) No. of Industries: 86 No. of Occupations: 102 No. of Employees: 363666 (estimated) No. of Female Employees: 186490 (estimated)

分子结构数据

1、  摩尔折射率：37.25

2、  摩尔体积（cm³/mol）：104.0

3、  等张比容（90.2K）：312.7

4、  表面张力（dyne/cm）：81.7

5、  极化率（10-24cm3）：14.76

计算化学数据

1、   疏水参数计算参考值（XlogP）：-2.6

2、   氢键供体数量：5

3、   氢键受体数量：6

4、   可旋转化学键数量：1

5、   互变异构体数量：

6、   拓扑分子极性表面积（TPSA）：110

7、   重原子数量：12

8、   表面电荷：0

9、   复杂度：151

10、同位素原子数量：0

11、确定原子立构中心数量：4

12、不确定原子立构中心数量：1

13、确定化学键立构中心数量：0

14、不确定化学键立构中心数量：0

15、共价键单元数量：1

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