氯化氰

外观与性状：

无色,液体/气体

密度：

1.234 g/cm3

熔点：

6.5ºC

沸点：

14°C

折射率：

1.376

存储条件/存储方法：

库房通风低温干燥,轻装轻卸

稳定性相关：

1.稳定性^[12]   稳定

2.禁配物^[13]   水、碱类、醇类、酸类

3.避免接触的条件^[14]   受热、潮湿空气

4.聚合危害^[15]   不聚合

5.分解产物^[16]   氯化氢、氰化氢

其它信息：

1.性状：无色液体或气体，有催泪性。^[1]

2.熔点（℃）：-6.5~-6^[2]

3.沸点（℃）：12.5~13.1^[3]

4.相对密度（水=1）：1.186^[4]

5.相对蒸气密度（空气=1）：2.16^[5]

6.饱和蒸气压（kPa）：134.63（20℃）^[6]

7.临界压力（MPa）：5.99^[7]

8.辛醇/水分配系数：-0.38^[8]

9.溶解性：溶于水、乙醇、乙醚等多数有机溶剂。^[9]

风险类别：

2.3

海关代码：

2853002000

WGK_Germany：

3
德国有关水污染物质的分类清单

危险类别码：

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

安全说明：

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing .

危险标志：

T: Toxic;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

GT2275000

CHEMICAL NAME :

Cyanogen chloride

CAS REGISTRY NUMBER :

506-77-4

BEILSTEIN REFERENCE NO. :

0969190

LAST UPDATED :

199712

DATA ITEMS CITED :

29

MOLECULAR FORMULA :

C-Cl-N

MOLECULAR WEIGHT :

61.47

WISWESSER LINE NOTATION :

G CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human

DOSE/DURATION :

10 mg/m3

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - chronic pulmonary edema

REFERENCE :

WHOTAC World Health Organization, Technical Report Series. (WHO, 1211 Geneva, 27, Switzerland) No.1- 1950- Volume(issue)/page/year: -,31,1970

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

2 gm/m3

TOXIC EFFECTS :

Skin and Appendages - primary irritation (after topical exposure)

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

5 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

3300 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - cat

DOSE/DURATION :

6 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

20 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

3150 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Bird - pigeon

DOSE/DURATION :

8700 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Mammal - domestic

DOSE/DURATION :

2970 ug/kg

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508 *** REVIEWS *** ACGIH TLV-CL 0.75 mg/m3 (0.3 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.3 ppm (0.6 mg/m3) JAN 1993 OEL-BELGIUM:STEL 0.3 ppm (0.75 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.1 ppm (0.3 mg/m3) JAN 1993 OEL-FINLAND:STEL 0.1 ppm (0.3 mg/m3);Skin JAN 1993 OEL-FRANCE:STEL 0.3 ppm (0.6 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 0.3 ppm (0.6 mg/m3) JAN 1993 OEL-SWEDEN:TWA 0.1 ppm (0.3 mg/m3);STEL 0.3 ppm (0.8 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.3 ppm (0.8 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.3 ppm (0.6 mg/m3);STEL 0.3 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CYANOGEN CHLORIDE-air:CL 0.3 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84337 No. of Facilities: 34 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 134 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84337 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1391 (estimated)

毒理学数据：

1.急性毒性^[10]

LD50：6mg/kg（猫经口）

LC50：3124ppm（大鼠吸入，60min）；4701ppm（大鼠吸入，30min）

2.刺激性  暂无资料

生态数据：

1.生态毒性  暂无资料

2.生物降解性  暂无资料

3.非生物降解性  暂无资料

4.其他有害作用^[11]  该物质对环境有危害，应特别注意对水体的污染。

分子结构数据

1、摩尔折射率：11.44

2、摩尔体积（cm³/mol）：49.8

3、等张比容（90.2K）：118.6

4、表面张力（dyne/cm）：32.2

5、极化率（10-24cm3）：4.53

计算化学数据

1.疏水参数计算参考值（XlogP）:1

2.氢键供体数量:0

3.氢键受体数量:1

4.可旋转化学键数量:0

5.互变异构体数量:无

6.拓扑分子极性表面积23.8

7.重原子数量:3

8.表面电荷:0

9.复杂度:31.3

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1