压力克

外观与性状：

白色结晶粉末

密度：

1.35

熔点：

93°C

沸点：

2ºC

闪点：

2 °C

水溶解性：

READILY 可溶

折射率：

1.475

存储条件/存储方法：

库房通风低温干燥,与碱类、食品添加剂分开存放

稳定性相关：

如果遵照规格使用和储存则不会分解，未有已知危险反应

其它信息：

1.         性状：白色晶体

2.         密度（g/mL,20℃）：1.35

3.         相对蒸汽密度（g/mL,空气=1）：未确定

4.         熔点（ºC）：90-91

5.         沸点（ºC,常压）：147

6.         沸点（ºC,KPa）：未确定

7.         折射率：未确定

8.         闪点（ºC）：2

9.         比旋光度（º）：未确定

10.      自燃点或引燃温度（ºC）：未确定

11.      蒸气压（Pa,24ºC）：2.266×10-1

12.      饱和蒸气压（KPa,20ºC）：未确定

13.      燃烧热（KJ/mol）：未确定

14.      临界温度（ºC）：未确定

15.      临界压力（KPa）：未确定

16.      油水（辛醇/水）分配系数的对数值：未确定

17.      爆炸上限（%,V/V）：未确定

18.      爆炸下限（%,V/V）：未确定

19.     溶解性：可溶于水，易溶于甲醇、乙醇、丙酮、二氯乙烷、二氯甲烷，稍溶于苯、甲苯、二甲苯，在酒精、丙酮中溶解度为65%

包装等级：

I; II; III

风险类别：

6.1

海关代码：

2929909012

WGK_Germany：

3
德国有关水污染物质的分类清单

危险类别码：

R22

安全说明：

2-36-36/37-16

RTECS号：

TB4760000

危险标志：

Xn:Harmful

CHEMICAL IDENTIFICATION

RTECS NUMBER :

TB4760000

CHEMICAL NAME :

Phosphoramidothioic acid, N-acetyl-, O,S-dimethyl ester

CAS REGISTRY NUMBER :

30560-19-1

LAST UPDATED :

199710

DATA ITEMS CITED :

40

MOLECULAR FORMULA :

C4-H10-N-O3-P-S

MOLECULAR WEIGHT :

183.18

WISWESSER LINE NOTATION :

1VMPO&S1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

700 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>2500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

233 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2200 mg/m3/5H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

681 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - chicken

DOSE/DURATION :

800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Bird - chicken

DOSE/DURATION :

568 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - duck

DOSE/DURATION :

350 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

321 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - domestic

DOSE/DURATION :

106 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - wild bird species

DOSE/DURATION :

140 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

14580 mg/kg/90D-C

TOXIC EFFECTS :

Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1050 mg/kg/15W-I

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Autonomic Nervous System - sympathomimetic Biochemical - Metabolism (Intermediary) - amino acids (including renal excretion)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

33600 mg/kg/8W-I

TOXIC EFFECTS :

Liver - other changes Biochemical - Metabolism (Intermediary) - other proteins

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

15 mg/kg/5D-C

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

13500 mg/kg/90D-I

TOXIC EFFECTS :

Liver - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

150 mg/kg

SEX/DURATION :

male 5 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

200 mg/kg

SEX/DURATION :

male 5 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :

Micronucleus test

TYPE OF TEST :

Cytogenetic analysis

TYPE OF TEST :

Dominant lethal test

TYPE OF TEST :

Sperm Morphology

MUTATION DATA

TYPE OF TEST :

Sister chromatid exchange

TEST SYSTEM :

Rodent - hamster Ovary

DOSE/DURATION :

2 gm/L

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB84-138973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T0473 No. of Facilities: 196 (estimated) No. of Industries: 2 No. of Occupations: 1 No. of Employees: 770 (estimated) No. of Female Employees: 378 (estimated)

毒理学数据：

 大鼠经口LD50：700mg/kg。雌性为866mg/kg；兔急性经皮LD50＜2000mg/kg。98%原药以300mg/kg剂量喂养大鼠3个月无影响。以100mg/kg掺入饲料，喂养狗2年，未发现三致（致癌、致畸、致突变）作用。红鲤鱼LD50为104mg/L（48h），白鲢为485mg/L（48h）。雄野鸭急性经口LD50为350mg/kg，小鸡为852mg/kg。

生态数据：

若无政府许可，勿将材料排入周围环境。

中国海关编码：2929909012

概述：

2929909012 异柳磷、甲基异柳磷、丙胺氟磷等 退税率:0.0% 监管条件:S(进出口农药登记证明)

申报要素：

品名, 成分含量, 用途

监管条件：

S.进出口农药登记证明

摘要/Summary：

2929909012 isopropyl 2-((ethoxy(isopropylamino)phosphorothioyl)oxy)benzoate

分子结构数据

1、   摩尔折射率：40.82

2、   摩尔体积（cm³/mol）：144.9

3、   等张比容（90.2K）：366.7

4、   表面张力（dyne/cm）：40.9

5、   介电常数（F/m）：

6、   偶极距（D）：

7、   极化率（10^-24cm³）：16.18

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:1

3.氢键受体数量:4

4.可旋转化学键数量:3

5.互变异构体数量:3

6.拓扑分子极性表面积80.7

7.重原子数量:10

8.表面电荷:0

9.复杂度:172

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:1

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

• 
  乙酰甲胺磷质谱(MS)