灭多威

外观与性状：

白色结晶固体

密度：

1.17 g/cm3

熔点：

78°C

沸点：

144°C

水溶解性：

Soluble. 5.8 g/100 mL

折射率：

1.508

存储条件/存储方法：

库房通风低温干燥,与食品原料分开储运

其它信息：

1. 性状：白色结晶，稍有硫黄味.

2. 密度（g/mL,25/4℃）：未确定

3. 相对蒸汽密度（g/mL,空气=1）：1.295

包装等级：

II

风险类别：

6.1(a)

海关代码：

2930909052

危险类别码：

R28;R50/53

安全说明：

S1/2-S22-S36/37-S60-S61-S45-S16

RTECS号：

AK2975000

危险标志：

T+:Verytoxic;N:Dangerous for the environment;

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AK2975000

CHEMICAL NAME :

Acetimidic acid, thio-N-((methylcarbamoyl)oxy)-, methyl ester

CAS REGISTRY NUMBER :

16752-77-5

LAST UPDATED :

199712

DATA ITEMS CITED :

52

MOLECULAR FORMULA :

C5-H10-N2-O2-S

MOLECULAR WEIGHT :

162.23

WISWESSER LINE NOTATION :

1SY1&UNOVM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

17 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

77 ppm/4H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>1600 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

9 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

20 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Primate - monkey

DOSE/DURATION :

40 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

5880 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

15 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - pigeon

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - chicken

DOSE/DURATION :

28 mg/kg

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - quail

DOSE/DURATION :

23700 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Bird - quail

DOSE/DURATION :

3680 ppm

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - duck

DOSE/DURATION :

15 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

SHELL* Shell Chemical Company. (P.O. Box 4320, Houston, TX 77210)

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Bird - duck

DOSE/DURATION :

1890 ppm

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - wild bird species

DOSE/DURATION :

10 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

15960 mg/kg/95W-C

TOXIC EFFECTS :

Blood - changes in bone marrow (not otherwise specified) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

264 mg/kg/33D-I

TOXIC EFFECTS :

Brain and Coverings - other degenerative changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

18200 mg/kg/2Y-C

TOXIC EFFECTS :

Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

3 gm/kg/3W-I

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Related to Chronic Data - death

TYPE OF TEST :

DNA damage

TYPE OF TEST :

DNA damage

TYPE OF TEST :

Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

REFERENCE :

ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 42,362,1987 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 2.5 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW 85ALAU "Carbamate Insecticides: Chemistry, Biochemistry, and Toxicology," Kuhr, R.J., and H.W. Dorough, Cleveland, OH, CRC Press, 1976 Volume(issue)/page/year: -,106,1977 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 2.5 mg/m3 JAN 1993 OEL-BELGIUM:TWA 2.5 mg/m3 JAN 1993 OEL-DENMARK:TWA 2.5 mg/m3;Skin JAN 1993 OEL-FRANCE:TWA 2.5 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 2.5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 2.4 mg/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 2.5 mg/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHOMYL-air:10H TWA 2.5 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - B0027 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 2367 (estimated) No. of Female Employees: 1288 (estimated)

毒理学数据：

雄性大鼠经口LD50：17mg/kg,雌24mg/kg。原药对兔急性经皮LD50>5000mg /kg。大鼠急性吸入LC50为0.3mg/L(4h).鳃鱼、金鱼的LC50分别为3.4mg/L, 0.87mg/L, 0.lmg/L (96h)0野鸭急性经日LD50为16 mg /kg。

中国海关编码：2930909052

概述：

2930909052 灭多威、涕灭威、乙硫苯威等〔包括杀线威、甲硫威、多杀威、涕灭砜威、硫双威、〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:0.0%。最低关税:6.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途

监管条件：

S.进出口农药登记证明

摘要/Summary：

2930909052 (e)-2-methyl-2-(methylsulfonyl)propanal o-methylcarbamoyl oxime。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:0.0%。MFN tarrif:6.5%。general tariff:30.0%

分子结构数据

1、   摩尔折射率：41.18

2、   摩尔体积（cm³/mol）：137.9

3、   等张比容（90.2K）：338.6

4、   表面张力（dyne/cm）：36.3

5、   极化率（10^-24cm³）：16.32

计算化学数据

1、 疏水参数计算参考值（XlogP）:0.6

2、 氢键供体数量：1

3、 氢键受体数量：3

4、 可旋转化学键数量: 3

5、 互变异构体数量：2

6、 拓扑分子极性表面积（TPSA）:50.7

7、 重原子数量：10

8、 表面电荷：0

9、 复杂度：147

10、 同位素原子数量：0

11、 确定原子立构中心数量：0

12、 不确定原子立构中心数量：0

13、 确定化学键立构中心数量：1

14、 不确定化学键立构中心数量：0

15、 共价键单元数量：1

• 
  灭多威红外图谱(IR1)
• 
  灭多威红外图谱(IR2)
• 
  灭多威质谱(MS)
• 
  灭多威核磁图(¹³CNMR)
• 
  灭多威核磁图(¹HNMR)