N-甲基-2-丙烯酰胺

密度：

0.89 g/cm3

沸点：

207.7ºC at 760 mmHg

闪点：

103.6ºC

折射率：

1.414

蒸汽压：

0.222mmHg at 25°C

其它信息：

1.密度（g/cm3）：0.89

2.沸点（760 mmHg,ºC）：207.7

3.闪点（ºC）：103.6

包装等级：

III

风险类别：

6.1(b)

海关代码：

2924199090

危险类别码：

R20/21/22

安全标志：

S23:不要吸入蒸汽。
S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
:

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AS3676000

CHEMICAL NAME :

Acrylamide, N-methyl-

CAS REGISTRY NUMBER :

1187-59-3

BEILSTEIN REFERENCE NO. :

1737696

LAST UPDATED :

199701

DATA ITEMS CITED :

11

MOLECULAR FORMULA :

C4-H7-N-O

MOLECULAR WEIGHT :

85.12

WISWESSER LINE NOTATION :

1U1VM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

476 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

477 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

6500 mg/kg/13W-I

TOXIC EFFECTS :

Peripheral Nerve and Sensation - structural change in nerve or sheath Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4988 mg/kg/18W-C

TOXIC EFFECTS :

Behavioral - muscle weakness

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2587 mg/kg/8W-I

TOXIC EFFECTS :

Related to Chronic Data - changes in testicular weight

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

2544 mg/kg

SEX/DURATION :

male 16 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

595 gm/kg

SEX/DURATION :

male 5 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

595 gm/kg

SEX/DURATION :

male 5 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

MUTATION DATA

TEST SYSTEM :

Rodent - mouse

DOSE/DURATION :

596 mg/kg/5W (Continuous)

REFERENCE :

ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 59,201,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1046 No. of Facilities: 122 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 367 (estimated)

中国海关编码：2924199090

概述：

2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 包装

摘要/Summary：

2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

计算化学数据

1.疏水参数计算参考值（XlogP）:0.1

2.氢键供体数量:1

3.氢键受体数量:1

4.可旋转化学键数量:1

5.互变异构体数量:2

6.拓扑分子极性表面积29.1

7.重原子数量:6

8.表面电荷:0

9.复杂度:67.9

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1