二苯并环辛烯PEG马来酰亚胺,DBCO-PEG-MAL，DBCO-PEG-Maleimide，芃硕生物强势推出，自主研发，欢迎选购！
|
名称 |
货号 |
英文名、缩写 |
分子量 |
规格 |
|
DBCO-PEG-MAL |
PS2-MDB-5K |
DBCO-PEG-MAL |
5000 |
0.1g、0.5g |
|
DBCO-PEG-MAL |
PS2-MDB-2K |
DBCO-PEG-MAL |
2000 |
0.1g、0.5g |
|
DBCO-PEG-MAL |
PS2-MDB-3K |
DBCO-PEG-MAL |
3400 |
0.1g、0.5g |
|
DBCO-PEG-MAL |
PS2-MDB-1K |
DBCO-PEG-MAL |
1000 |
0.1g、0.5g |
|
DBCO-PEG-MAL |
PS2-MDB-10K |
DBCO-PEG-MAL |
10000 |
0.1g、0.5g |
（备注：非常规分子量：400、600。精确聚合度的小分子定制。）
结构式：
基本信息：
中文名称：二苯并环辛烯-聚乙二醇-马来酰亚胺 (DBCO-PEG-MAL)
别名：DBCO-PEG-Maleimide
英文名称：DBCO-PEG-Maleimide，DBCO-PEG-MAL
CAS：-
分子量：400、600、1K、2K、3.4K、4K、5K、10K
纯度：95%以上
二苯并环辛烯PEG马来酰亚胺,DBCO-PEG-MAL，DBCO-PEG-Maleimide，芃硕生物强势推出，自主研发，欢迎选购！
应用简介：
Maleimide PEG DBCO (dibenzocycolctyne) is one of Ponsure DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aqueous solution. DBCO PEG derivatives possess fast kinetics stability in aqueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need ftoxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility stability reduce immunogenicity of peptides proteins. It can also suppress the non-specific binding ofged molecules to the modified surfaces.
Copper-free Click Reaction Procedures:
Prepare the azide-containing reagents in reaction buffer.
Add DBCO reagents to azide containing reagents. Add 1 mol equivalent of limiting reagent to 1.5~3.0 mol equivalents of abundance reagent.
Incubate the reaction at room temperature f2~4 hours 2~12 hours at 4℃.
Purify conjugates either by dialysis size-exclusionomatograph.
物理性质：
状态：淡黄色到黄色固体，或者半固体，取决于分子量。
溶解性：溶于DMSO,DMF等溶剂。
保持条件：-20℃长期保存，避光，干燥。
注意事项：取用一定要干燥，避免频繁的溶解和冻干。
反应性：DBCO与含有N3基团的反应。MAL可以和SH。
二苯并环辛烯PEG马来酰亚胺,DBCO-PEG-MAL，DBCO-PEG-Maleimide，芃硕生物强势推出，自主研发，欢迎选购！
技术指标：
纯度（PEG）：95%以上
取代率（DBCO）：90%以上
取代率（MAL）：90%以上
分散系数（PDI）：小于等于1.05
分析：COA、GPC、NMR、MALDI-TOF
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二苯并环辛烯PEG马来酰亚胺，DBCO-PEG-Maleimide，DBCO-PEG-MAL，产品芃硕生物强势推出，自主研发，欢迎选购！
