中文名称： D-色氨酸

中文别名： D-2-氨基-3-吲哚基丙酸; H-D-Trp-OH; D-(+)-色氨酸

英文名称： D-(+)-Tryptophan

英文别名： D-Tryptophan; (R)-2-Amino-3-(3-indolyl)propionic acid; H-D-Trp-OH; 3-(2,3-dihydro-1H-indol-3-yl)-D-alanine

CAS号： 153-94-6

EINECS号： 205-819-9

分子式： C11H12N2O2

分子量： 204.23

InChI： InChI:1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

分子结构：

密度： 1.232g/cm3

熔点： 282-285℃

沸点： 399.4°C at 760 mmHg

闪点： 195.4°C

水溶性： 11 g/L (20℃)

蒸汽压： 4.27E-07mmHg at 25°C

物化性质：

熔点 282-285℃

比旋光度 31.5° (c=1, H2O 24℃)

水溶性 11 g/L (20℃)

产品用途：

是重要的营养剂，医药上用作癞皮病的防治剂

D-色氨酸(英文D(+)-Tryptophan)在常温下为白色或类白色至微黄色的结晶性粉末，无臭或微臭，味稍甜。水中溶解度1.14克(25℃)，可溶于稀酸和稀碱，在碱中安稳，强酸中分化，微溶于乙醇，不溶于氯仿、乙醚，对人和动物的成长发育、推陈出新起重要的效果，被称为第二必需氨基酸 ，与L-型的物理化学性质几乎完全相同，仅旋光性相反，但它们的散布、功用及辅酶具有多样性，熔点很高，一般在200度以上，能溶于水，在 近紫外光区域有吸收光的才能。

D-色氨酸特性与效果：D-色氨酸作为一种非蛋白活性氨基酸，具有特别的生理学性质，在食物饲料工业以及农业中能够作为非养分甜味剂、饲料添加剂、植物成长剂 ，在医药行业中，首要用于组成各种多肽，替代L-色氨酸延伸肽类药物的半衰期并下降副效果，不致发作抗药性而成为酶按捺剂的重要组成前 体。能进步机体的免疫才能，推迟过敏性反应的发作。大多数多肽类抗生素能抗革兰氏阳性菌，也有的对革兰氏阴性菌如绿脓杆菌、分枝杆菌 、真菌、病菌、病菌和肿瘤细胞等有较好的按捺或杀灭效果。

用D-色氨酸组成半组成抗生素，其侧链关于其药理功用起着重要的效果，肽键很难被β-内酰酶效果，然后有较高的安稳性，并且有抗菌谱广， 毒性小，过敏性低，吸收快，血浓度高，药力继续时间长等。

English name ： D-(+)-Tryptophan

English alias ： D-Tryptophan; (R)-2-Amino-3-(3-indolyl)propionic acid; H-D-Trp-OH; 3-(2,3-dihydro-1H-indol-3-yl)-D-alanine

CAS： 153-94-6

EINECS： 205-819-9

Molecular： C11H12N2O2

Molecular weight ： 204.23

InChI： InChI:1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)

Molecular structure ： D-(+)-Tryptophan 153-94-6

Density： 1.232g/cm3

Melting point： 282-285℃

Boiling point： 399.4°C at 760 mmHg

Flash point： 195.4°C

Water soluble： 11 g/L (20℃)

Steam pressure： 4.27E-07mmHg at 25°C

Ratio of spin 31.5° (c=1, H2O 24℃)

Water soluble 11 g/L (20℃)

Product use ：

Is an important nutrient. M

edically used as a prevention treatment agent fspitdisease

D-tryptophan (English D(-Tryptophan) crystalline powder white white-like to slightly yellow at room temperature，No odslight odor, slightly sweeter taste。Dissolved 1.14 g (25 degrees C) in water，Soluble in dilute acids alkalis，Stable in alkali, differentiation in strong acid, slightly soluble in ethanol, insoluble in chloroform、Ether，Important effecton on the growth development of humans animals，known as the second essential amino acid ，Almost identical to the physical chemical properties of the L-type，Only the opposite of the spin，But their dispersion, function, coenzyme are diverse.Melting point is very high, generally in more than 200 degrees, soluble in water, in the near ultraviolet light area has the ability to absorb light.

D-tryptophanacteristics effects:D-tryptophan, as a non-proteinactive amino acid, has a special physiological properties.Can be used as a non-nutrient sweetener, feed additive, plant growth agent in the food feed industry agriculture .In the pharmaceutical industry, the primary use is to form a variety of peptides，Substitute L-tryptophan extended peptide drugs with half-life decreased side effects，The precursof enzyme-pressing agent without anti-drug resistance.Can improve the body's immune ability, delay the onset of allergic reactions。Most peptide antibiotics are resistant to gram-positive bacteria, some have vegmy-negative bacteria such as chlorella, mycobacterium, fungi, germs, germs tumcells.Better press kill effect.

Semi-composed antibiotics made up of D-tryptophan，Its side chain plays an important role in its pharmacological function，Peptide bonds are difficult to be beta-containitolase effects，then there's a higher degree of stability.，there is a broad antibacterial spectrum, small toxicity, hypoallergenic, rapid absorption, high blood concentration, drug strength continues fa long time, etc.