阿卡地新,_成都云希化工有限公司

阿卡地新(2627-69-2)

现现货供应

CAS NO：: 2627-69-2

纯度：

规格：: 1克

价格：: 洽谈

: 马上询价

基本信息

产品名称：阿卡地新; 5-氨基-1-beta-D-呋喃核糖基-1H-咪唑-4-甲酰胺
CAS NO：2627-69-2
中文别名：5-Amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide; Aicar
分子式：C₉H₁₄N₄O₅
分子量：258.23
英文名称：1H-Imidazole-4-carboxamide,5-amino-1-b-D-ribofuranosyl-
EINECS：220-097-5
密度：2.06 g/cm3
英文别名：Imidazole-4-carboxamide,5-amino-1-b-D-ribofuranosyl- (6CI,7CI,8CI);1-Ribosyl-4-carboxamido-5-aminoimidazole; 1-b-D-Ribofuranosyl-5-amino-4-imidazolecarboxamide;5-Amino-1-ribosyl-4-imidazolecarboxamide; 5-Amino-1-b-D-ribofuranosylimidazole-4-carboxamide;5-Amino-4-imidazolecarboxamide ribofuranoside; 5-Amino-4-imidazolecarboxamideriboside; 5-Aminoimidazole-4-carboxamide 1-(b-D-ribofuranoside); AIC-Riboside; AICA-Riboside;AICAR; Acadesine; Arasine; GP 1-110; NSC 105823
闪点：393.1oC
熔点：214-215°C
沸点：726.3oC at 760 mmHg
毒性：

详细信息

Product Name: AICAR 阿卡地新核苷酸甲酰胺

Alternate Name/Synonyms: 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; AICA-Riboside; NSC 105823
Peptide Sequence: N/A
Appearance: Tan powder
Formulation: N/A
CAS Number: 2627-69-2
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Purity: ≥98% by HPLC
Solubility:H?O
Storage Temp.: -20°C
Shipping Conditions: gel pack

Description: A cell- permeable activatof AMP-activated protein kinase (AMPK), a metabolic sensinvolved in both cellular whole body energy homeostasis. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise triggers insulin-independent glucose uptake by skeletal muscle. AICAR is able to activate the molecular circuitry of pluripotency in mESC to induce the expression of several key regulators of pluripotency in somatic cells. AMP-活化蛋白激酶（AMPK）的细胞渗透性激活剂，AMPK是参与细胞和全身能量平衡的代谢传感器。在体内，AMPK与AICAR的药理活性模拟运动并引发骨骼肌对胰岛素非依赖性葡萄糖的摄取。 AICAR能够激活mESC中多能性的分子回路并诱导体细胞中多种关键多能性调节因子的表达