乙胺,无水

外观与性状：

透明液体

密度：

0.81 g/mL at 20 °C

熔点：

-81 °C(lit.)

沸点：

17 °C

闪点：

48 °F

水溶解性：

miscible

折射率：

n20/D 1.384

蒸汽密度：

1.56 (15 °C, vs air)

存储条件/存储方法：

库房通风低温干燥,与氧化剂、酸类分开存放

稳定性相关：

1.化学性质：水溶液呈碱性，化学性质和甲胺相似。对光不稳定，在140~200℃时经紫外线照射，分解生成氢、氯、氨、甲烷和乙烷等。490~555℃于低压下进行热解，生成氢、氯、甲烷等。乙胺与次氯酸钠作用生成N-氯代乙胺。在乙胺水溶液中通入氯气，生成N,N-二氯乙胺，与金属钠、锶反应，生成金属的乙氨基化合物。

2.稳定性^[23]  稳定

3.禁配物^[24]  强氧化剂、强酸

4.聚合危害^[25]  不聚合

5.分解产物^[26]  氨

其它信息：

1.性状：无色、有强烈氨味的液体或气体。^[1]

2.熔点（℃）：-81^[2]

3.沸点（℃）：16.6^[3]

4.相对密度（水=1）：0.70^[4]

5.相对蒸气密度（空气=1）：1.56^[5]

6.饱和蒸气压（kPa）：121（20℃）^[6]

7.燃烧热（kJ/mol）：-1713.3^[7]

8.临界温度（℃）：182.9^[8]

9.临界压力（MPa）：5.62^[9]

10.辛醇/水分配系数：-0.13^[10]

11.闪点（℃）：-17（CC）；＜-6.7（OC）^[11]

12.引燃温度（℃）：385^[12]

13.爆炸上限（%）：14.0^[13]

14.爆炸下限（%）：3.5^[14]

15.溶解性：溶于水、乙醇、乙醚等。^[15]

包装等级：

II

风险类别：

3

海关代码：

2921193000

WGK_Germany：

1
德国有关水污染物质的分类清单

危险类别码：

R12;R36/37

安全说明：

S26-S29-S16-S45-S36/37-S7

RTECS号：

KH2100000

安全标志：

S16:远离火源。
S26:万一接触眼睛，立即使用大量清水冲洗并送医诊治。
S29:不要将残余物倾入排水口。

危险标志：

Xi:Irritant

CHEMICAL IDENTIFICATION

RTECS NUMBER :

KH2100000

CHEMICAL NAME :

Ethanamine

CAS REGISTRY NUMBER :

75-04-7

LAST UPDATED :

199712

DATA ITEMS CITED :

41

MOLECULAR FORMULA :

C2-H7-N

MOLECULAR WEIGHT :

45.10

WISWESSER LINE NOTATION :

Z2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,429,1986

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/25/1958

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 3,287,1951

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

REFERENCE :

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,429,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

400 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

5540 ppm/1H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - corneal damage Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538173

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

390 uL/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

350 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.) Volume(issue)/page/year: 4,1295,1935

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

2300 mg/m3

REFERENCE :

TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 14,80,1975 *** REVIEWS *** ACGIH TLV-STEL 27.6 mg/m3 (15 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 9.2 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924- Volume(issue)/page/year: 9,389,1931 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 10 ppm (18 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,103,1971 OSHA PEL (Gen Indu):8H TWA 10 ppm (18 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 10 ppm (18 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 10 ppm (18 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 10 ppm (18 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-BELGIUM:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-DENMARK:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-FINLAND:TWA 10 ppm (18 mg/m3);STEL 20 ppm (37 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 10 ppm (18 mg/m3);STEL 15 ppm (27 mg/m3) JAN 1993 OEL-GERMANY:TWA 10 ppm (18 mg/m3);Skin JAN 1993 OEL-JAPAN:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-POLAND:TWA 3 mg/m3 JAN 1993 OEL-RUSSIA:TWA 10 ppm JAN 1993 OEL-SWEDEN:TWA 10 ppm (18 mg/m3);STEL 15 ppm (30 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 10 ppm (18 mg/m3);STEL 20 ppm (36 mg/m3) JAN 1993 OEL-TURKEY:TWA 10 ppm (18 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 10 ppm (18 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ETHYLAMINE-air:10H TWA 10 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 31520 No. of Facilities: 205 (estimated) No. of Industries: 9 No. of Occupations: 11 No. of Employees: 4982 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 31520 No. of Facilities: 31 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1797 (estimated) No. of Female Employees: 357 (estimated)

毒理学数据：

1.急性毒性^[16]  LD50：400mg/kg（大鼠经口）；390mg/kg（兔经皮）

2.刺激性^[17]

家兔经皮：500mg（24h），轻度刺激。

家兔经眼：250μg（24h），或5mg，重度刺激。

3.亚急性与慢性毒性^[18]  家兔吸入184mg/m³，每次7h，每周5次，6周见肺大量出现，支气管周围炎及肾实质不同程度变性。从染毒2周开始，兔眼呈现上皮细胞糜烂和角膜水肿。

4.其他^[19]  LCLo：3000ppm（大鼠吸入，4h）

生态数据：

1.生态毒性^[20]

EC50：40mg/L（48h）（水蚤）

IC50：1.3~2.3mg/L（72h）（藻类）

2.生物降解性^[21]  MITI-I测试，初始浓度100ppm，污泥浓度30ppm，2周后降解59%~90%。

3.非生物降解性^[22]  空气中，当羟基自由基浓度为5.00×10⁵个/cm³时，降解半衰期为14h（理论）。

中国海关编码：2921193000

概述：

2921193000 N,N-二(2-氯乙基)乙胺。监管条件:3(两用物项和技术出口许可证)2(两用物项和技术出口许可证,两用物项和技术进口许可证)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

申报要素：

品名, 成分含量, 用途

监管条件：

3.两用物项和技术出口许可证2.两用物项和技术进口许可证

摘要/Summary：

2921193000 2-chloro-n-(2-chloroethyl)-n-ethylethanamine。supervision conditions:3(export license for dual-use item and technologies)2(export license for dual-use item and technologies,import license for dual-use item and technologies)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

分子结构数据

1、摩尔折射率：14.84

2、摩尔体积（cm³/mol）：65.2

3、等张比容（90.2K）：140.7

4、表面张力（dyne/cm）：21.5

5、极化率（10^-24cm³）：5.88

计算化学数据

1、疏水参数计算参考值（XlogP）：-0.3

2、氢键供体数量：1

3、氢键受体数量：1

4、可旋转化学键数量：0

5、互变异构体数量：

6、拓扑分子极性表面积（TPSA）：26

7、重原子数量：3

8、表面电荷：0

9、复杂度：2.8

10、同位素原子数量：0

11、确定原子立构中心数量：0

12、不确定原子立构中心数量：0

13、确定化学键立构中心数量：0

14、不确定化学键立构中心数量：0

15、共价键单元数量：1

• 
  乙胺红外图谱(IR1)
• 
  乙胺核磁图(¹³CNMR)
• 
  乙胺质谱(MS)