N-甲基-2-硝基苯胺

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
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  • 下游产品
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N-甲基-2-硝基苯胺 基本信息

中文名称:
N-甲基-2-硝基苯胺 
中文别名:
N-甲基-2-硝基苯胺;
鄰硝基甲胺苯;
N-甲邻硝苯胺 
英文名称:
Benzenamine,N-methyl-2-nitro-
英文别名:
N-METHYL-2-NITROANILINE;
o-nitro-N-methylaminobenzene;
o-nitro-N-methylaniline;
Aniline,N-methyl-o-nitro;
Benzenamine,N-methyl-2-nitro;
N-Methyl 2-nitroaniline;
o-(Methylamino)nitrobenzene;
N-Methyl-2-nitrobenzenamine;
2-methylamino-nitrobenzene;
2-Nitro-N-methylaniline;
N-Methyl-o-nitroaniline 
CAS No.:
612-28-2
分 子 式:
C7H8N2O2
分 子 量:
152.15
精确分子量:
152.05900
PSA:
57.85000
MDL:
MFCD00007090
EINECS:
210-303-1
InChI:
InChI=1/C7H8N2O2/c1-8-6-4-2-3-5-7(6)9(10)11/h2-5,8H,1H3
危险品标志:
T:Toxic
风险术语:
R23/24/25; R33;
安全术语:
S28A; S36/37; S45;
分子结构式:
SDS:
查看

N-甲基-2-硝基苯胺 物化性质

外观与性状:
红色粉末
密度:
1.26g/cm3
熔点:
35-38 °C(lit.)
沸点:
277.9ºC at 760 mmHg
闪点:
>230 °F
折射率:
1.619
存储条件/存储方法:

贮存:

将密器密封,储存密封的主藏器内,并放在阴凉, 干爽的位置。

稳定性相关:

性质与稳定性:

常温常压下,或不分解产物。

 

N-甲基-2-硝基苯胺 安全信息

包装等级:
II
风险类别:
6.1
WGK_Germany:
3
德国有关水污染物质的分类清单
危险类别码:
R23/24/25;R33
安全说明:
S36/37-S45
RTECS号:
BY5710000
安全标志:
S45:出现意外或者感到不适,立刻到医生那里寻求帮助(最好带去产品容器标签)。
:
危险标志:
T:Toxic;

N-甲基-2-硝基苯胺 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BY5710000
CHEMICAL NAME :
Aniline, N-methyl-o-nitro-
CAS REGISTRY NUMBER :
612-28-2
BEILSTEIN REFERENCE NO. :
2209110
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H8-N2-O2
MOLECULAR WEIGHT :
152.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
2500 ug/plate
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 23,695,1985
生态数据:

三、生态学数据:

1、其它有害作用:该物质对环境可能有危害,对水体应给予特别注意。

N-甲基-2-硝基苯胺 MSDS

  Material Safety Data Sheet

Section 1. Identification of the substance
    Product Name:      N-Methyl 2-nitroaniline    
    Synonyms:

Section 2. Hazards identification
    Harmful by inhalation, in contact with skin, and if swallowed.
    H301:        Toxic if swallowed    
    H311:        Toxic in contact with skin    
    H331:        Toxic if inhaled    
    H373:        May cause damage to organs through prolonged or repeated exposure    
    P261:        Avoid breathing dust/fume/gas/mist/vapours/spray    
    P280:        Wear protective gloves/protective clothing/eye protection/face protection    
    P301+P310:        IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician    
    P311:        Call a POISON CENTER or doctor/physician    

Section 3. Composition/information on ingredients.
    Ingredient name:        N-Methyl 2-nitroaniline    
    CAS number:        612-28-2    

Section 4. First aid measures
    Skin contact:        Immediately wash skin with copious amounts of water for at least 15 minutes while removing    
    contaminated clothing and shoes. If irritation persists, seek medical attention.
    Eye contact:        Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate    
    flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
    attention.
    Inhalation:        Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.    
    Ingestion:        Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.    

Section 5. Fire fighting measures
    In the event of a fire involving this material, alone or in combination with other materials, use dry
    powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
    should be worn.

Section 6. Accidental release measures
    Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
    standards.
    Respiratory precaution:        Wear approved mask/respirator    
    Hand precaution:        Wear suitable gloves/gauntlets    
    Skin protection:        Wear suitable protective clothing    
    Eye protection:        Wear suitable eye protection    
    Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
    for disposal. See section 12.
    Environmental precautions: Do not allow material to enter drains or water courses.

Section 7. Handling and storage
    Handling:        This product should be handled only by, or under the close supervision of, those properly qualified    
    in the handling and use of potentially hazardous chemicals, who should take into account the fire,
    health and chemical hazard data given on this sheet.
    Storage:        Store in closed vessels.    

Section 8. Exposure Controls / Personal protection
    Engineering Controls: Use only in a chemical fume hood.
    Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
    General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section 9. Physical and chemical properties
    Not specified
    Appearance:
    Boiling point:        No data    
    Melting point:        No data    
    Flash point:        No data    
    Density:        No data    
    Molecular formula:        C7H8N2O2    
    Molecular weight:        152.2    

Section 10. Stability and reactivity
    Conditions to avoid: Heat, flames and sparks.
    Materials to avoid: Oxidizing agents.
    Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section 11. Toxicological information
    No data.

Section 12. Ecological information
    No data.

Section 13. Disposal consideration
    Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
    disposal authority, in accordance with national and regional regulations.

Section 14. Transportation information
    UN Number:        UN2811 Class: 6.1 Packing group: II    
    Proper shipping name: TOXIC SOLIDS, ORGANIC, N.O.S. (N-Methyl 2-nitroaniline)

Section 15. Regulatory information
    No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
    302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
    Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

N-甲基-2-硝基苯胺 分子结构与计算化学数据

分子结构数据

五、分子性质数据:

1   摩尔折射率:42.40

2   摩尔体积(m3/mol):120.7

3   等张比容(90.2K):321.6

4   表面张力(dyne/cm):50.3

5 极化率(10-24cm3):16.81

计算化学数据

1.疏水参数计算参考值(XlogP):无

2.氢键供体数量:1

3.氢键受体数量:3

4.可旋转化学键数量:1

5.互变异构体数量:无

6.拓扑分子极性表面积57.8

7.重原子数量:11

8.表面电荷:0

9.复杂度:144

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1

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