番茄红素

  • 基本信息
  • 制备方法及用途
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 结构与计算化学
  • 上游产品
  • 下游产品

番茄红素 基本信息

中文名称:
番茄红素 
中文别名:
番茄红素;
ψ,ψ-Carotene;
西红柿红素;
茄红素 
英文名称:
lycopene from tomato
英文别名:
lycopene;
LYCOVIT;
Lycopene,Redivivo;
all-trans-Lyc;
Lycopin;
Lycopen;
Lycopene;
4,4-CAROTENE;
LYCOSOURCE;
Y,Y-CAROTENE;
E 160d 
CAS No.:
502-65-8
分 子 式:
C40H56
分 子 量:
536.88
精确分子量:
536.43800
PSA:
0.00000
MDL:
MFCD00017350
EINECS:
207-949-1
InChI:
InChI=1/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21-,36-22+,37-27-,38-28-,39-29-,40-30+
危险品标志:
irritantxi
风险术语:
R36/37/38;
安全术语:
S26;S36/37/39;
分子结构式:
SDS:
查看

番茄红素 制备方法及用途

制备方法

可采用三孢布拉氏霉的两性菌株发酵生产β 胡萝卜素。将三孢布拉氏霉的“+”和“-”菌株分别在液体培养基中26℃培养48h,将各培养液分别添加于发酵培养基中,用量各为10%左右,发酵两天后,加入β 紫罗兰酮,于发酵温度26~28℃,pH=5 7~7 0条件下再发酵3~6天。然后将培养物用湿热杀死(100℃中10~15min),以阻止胡萝卜素的再发酵分解。发酵培养基中含有油脂,在发酵过程中产生的胡萝卜素溶解在油中,故发酵结束后将菌体过滤掉,胡萝卜素即存在于滤液中。滤液在50~55℃真空干燥,然后用石油醚萃取,再上柱层析,浓缩收集液后即得β 胡萝卜素。 “+”菌株→培养“-”菌株→培养发酵加热过滤 真空干燥萃取柱层析浓缩产品

合成制备方法

可采用三孢布拉氏霉的两性菌株发酵生产β胡萝卜素。将三孢布拉氏霉的“+”和“-”菌株分别在液体培养基中26℃培养48h,将各培养液分别添加于发酵培养基中,用量各为10%左右,发酵两天后,加入β紫罗兰酮,于发酵温度2628℃,pH=5770条件下再发酵36天。然后将培养物用湿热杀死(100℃中1015min),以阻止胡萝卜素的再发酵分解。发酵培养基中含有油脂,在发酵过程中产生的胡萝卜素溶解在油中,故发酵结束后将菌体过滤掉,胡萝卜素即存在于滤液中。滤液在5055℃真空干燥,然后用石油醚萃取,再上柱层析,浓缩收集液后即得β胡萝卜素。

+”菌株→培养“-”菌株→培养发酵加热过滤

真空干燥萃取柱层析浓缩产品

用途简介

可用作食品添加剂和着色剂。还可作为医疗保健品,用于治疗维生素A缺乏症。另外也可作为饲料添加剂。

用途

可用作食品添加剂和着色剂。还可作为医疗保健品,用于治疗维生素A缺乏症。另外也可作为饲料添加剂。

番茄红素 物化性质

外观与性状:
暗红色细粉末或油状
密度:
0.888 g/cm3
熔点:
172-173°C
沸点:
660.9ºC
闪点:
350.7ºC
折射率:
1.53
存储条件/存储方法:

塑料袋装,外用纸箱包装,密封遮光贮存于阴凉、干燥处。避免吸潮。不得与有害有毒物质混存共放

稳定性相关:

按规格使用和贮存,不会发生分解,避免与氧化物接触

其它信息:

1.      性状:紫红色或暗红色晶体粉末

番茄红素 安全信息

海关代码:
3203001990
WGK_Germany:
3
德国有关水污染物质的分类清单
危险类别码:
R36/37/38
安全说明:
26-36/37/39
危险标志:
Xi: Irritant;

番茄红素 毒理性

毒理学数据:

暂无

生态数据:

通常对水是不危害的,若无政府许可,勿将材料排入周围环境。

番茄红素 MSDS


SECTION 1: Identification of the substance/mixture and of the company/undertaking
  Product identifiers
    Product name        : Lycopene    
    REACH No.        : A registration number is not available for this substance as the substance    
    or its uses are exempted from registration, the annual tonnage does not
    require a registration or the registration is envisaged for a later
    registration deadline.
    CAS-No.        : 502-65-8    
  Relevant identified uses of the substance or mixture and uses advised against
    Identified uses        : Laboratory chemicals, Manufacture of substances    
  
  

SECTION 2: Hazards identification
  Classification of the substance or mixture
    Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008
    Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.
  Label elements
    The product does not need to be labelled in accordance with EC directives or respective national laws.
  Other hazards - none

SECTION 3: Composition/information on ingredients
  Substances
    : ψ,ψ-Carotene
    Synonyms
    2,6,10,14,19,23,27,31-Octamethyl-dotriaconta-
    2,6,8,10,12,14,16,18,20,22,24,26,30-tridecaene
    Formula        : C40H56    
    Molecular Weight        : 536,87 g/mol    
    CAS-No.        : 502-65-8    
    EC-No.        : 207-949-1    
    No components need to be disclosed according to the applicable regulations.

SECTION 4: First aid measures
  Description of first aid measures
  If inhaled
    If breathed in, move person into fresh air. If not breathing, give artificial respiration.
  In case of skin contact
    Wash off with soap and plenty of water.
  In case of eye contact
    Flush eyes with water as a precaution.
  If swallowed
    Never give anything by mouth to an unconscious person. Rinse mouth with water.
  Most important symptoms and effects, both acute and delayed
    The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
    section 11
  Indication of any immediate medical attention and special treatment needed
    no data available

SECTION 5: Firefighting measures
  Extinguishing media
  Suitable extinguishing media
    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
  Special hazards arising from the substance or mixture
    Carbon oxides
  Advice for firefighters
    Wear self contained breathing apparatus for fire fighting if necessary.
  Further information
    no data available

SECTION 6: Accidental release measures
  Personal precautions, protective equipment and emergency procedures
    Avoid dust formation. Avoid breathing vapours, mist or gas.
    For personal protection see section 8.
  Environmental precautions
    Do not let product enter drains.
  Methods and materials for containment and cleaning up
    Sweep up and shovel. Keep in suitable, closed containers for disposal.
  Reference to other sections
    For disposal see section 13.

SECTION 7: Handling and storage
  Precautions for safe handling
    Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire
    protection.
    For precautions see section 2.2.
  Conditions for safe storage, including any incompatibilities
    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
    Recommended storage temperature: -70 °C
  Specific end use(s)
    A part from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
  Control parameters
  Components with workplace control parameters
  Exposure controls
  Appropriate engineering controls
    General industrial hygiene practice.
  Personal protective equipment
  Eye/face protection
    Use equipment for eye protection tested and approved under appropriate government standards
    such as NIOSH (US) or EN 166(EU).
  Skin protection
    Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
    (without touching glove's outer surface) to avoid skin contact with this product. Dispose of
    contaminated gloves after use in accordance with applicable laws and good laboratory practices.
    Wash and dry hands.
    The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
    the standard EN 374 derived from it.
  Body Protection
    Choose body protection in relation to its type, to the concentration and amount of dangerous
    substances, and to the specific work-place., The type of protective equipment must be selected
    according to the concentration and amount of the dangerous substance at the specific workplace.
  Respiratory protection
    Respiratory protection is not required. Where protection from nuisance levels of dusts are desired,
    use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and
    approved under appropriate government standards such as NIOSH (US) or CEN (EU).
  Control of environmental exposure
    Do not let product enter drains.

SECTION 9: Physical and chemical properties
  Information on basic physical and chemical properties
    a) Appearance        Form: solid    
    b) Odour        no data available    
    c) Odour Threshold        no data available    
    d) pH        no data available    
    e) Melting point/freezing        no data available    
    point
    f) Initial boiling point and no data available
    boiling range
    g) Flash point        no data available    
    h) Evapouration rate        no data available    
    i) Flammability (solid, gas) no data available
    j) Upper/lower        no data available    
    flammability or
    explosive limits
    k) Vapour pressure        no data available    
    l) Vapour density        no data available    
    m) Relative density        no data available    
    n) Water solubility        no data available    
    o) Partition coefficient: n- no data available
    octanol/water
    p) Auto-ignition        no data available    
    temperature
    q) Decomposition        no data available    
    temperature
    r) Viscosity        no data available    
    s) Explosive properties        no data available    
    t) Oxidizing properties        no data available    
  Other safety information
    no data available

SECTION 10: Stability and reactivity
  Reactivity
    no data available
  Chemical stability
    Stable under recommended storage conditions.
  Possibility of hazardous reactions
    no data available
  Conditions to avoid
    no data available
  Incompatible materials
    Strong oxidizing agents
  Hazardous decomposition products
    Other decomposition products - no data available
    In the event of fire: see section 5

SECTION 11: Toxicological information
  Information on toxicological effects
  Acute toxicity
    no data available
  Skin corrosion/irritation
    no data available
  Serious eye damage/eye irritation
    no data available
  Respiratory or skin sensitisation
    no data available
  Germ cell mutagenicity
    no data available
  Carcinogenicity
    IARC:        No component of this product present at levels greater than or equal to 0.1% is identified as    
    probable, possible or confirmed human carcinogen by IARC.
  Reproductive toxicity
    no data available
  Specific target organ toxicity - single exposure
    no data available
  Specific target organ toxicity - repeated exposure
    no data available
  Aspiration hazard
    no data available
  Additional Information
    RTECS: Not available
    To the best of our knowledge, the chemical, physical, and toxicological properties have not been
    thoroughly investigated.

SECTION 12: Ecological information
  Toxicity
    no data available
  Persistence and degradability
    no data available
  Bioaccumulative potential
    no data available
  Mobility in soil
    no data available
  Results of PBT and vPvB assessment
    PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
  Other adverse effects
    no data available

SECTION 13: Disposal considerations
  Waste treatment methods
  Product
    Offer surplus and non-recyclable solutions to a licensed disposal company.
  Contaminated packaging
    Dispose of as unused product.

SECTION 14: Transport information
  UN number
    ADR/RID: -        IMDG: -        IATA: -    
  UN proper shipping name
    ADR/RID: Not dangerous goods
    IMDG: Not dangerous goods
    IATA:        Not dangerous goods    
  Transport hazard class(es)
    ADR/RID: -        IMDG: -        IATA: -    
  Packaging group
    ADR/RID: -        IMDG: -        IATA: -    
  Environmental hazards
    ADR/RID: no        IMDG Marine pollutant: no        IATA: no    
  Special precautions for user
    no data available



SECTION 15 - REGULATORY INFORMATION
N/A


SECTION 16 - ADDITIONAL INFORMATION
N/A

番茄红素 分子结构与计算化学数据

分子结构数据

1  摩尔折射率:186.85

2  摩尔体积m3/mol604.2

3  等张比容(90.2K):1426.7

4  表面张力dyne/cm31.0

5  极化率10-24cm374.07

计算化学数据

1、  疏水参数计算参考值(XlogP):15.6

2、  氢键供体数量:0

3、  氢键受体数量:0

4、  可旋转化学键数量:16

5、  互变异构体数量:

6、  拓扑分子极性表面积(TPSA):0

7、  重原子数量:40

8、  表面电荷:0

9、  复杂度:1050

10、  同位素原子数量:0

11、  确定原子立构中心数量:0

12、  不确定原子立构中心数量:0

13、  确定化学键立构中心数量:11

14、  不确定化学键立构中心数量:0

15、  共价键单元数量:1

推荐供应商更多供应商>>

湖北鑫鸣泰化学有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:99% 包装信息:100kg,200kg 价格:1.0元 - 1.0元
联系方式:
联系人:黄 电话:027-50662354 手机:13264726139

中山联久生物科技有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:5% 包装信息:1/铝箔袋kg 价格:洽谈
联系方式:
联系人:王彩 电话:18125350267 手机:18125350267

湖北鑫鸣泰化学有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:99% 包装信息:25/桶kg 价格:洽谈
联系方式:
联系人:刘经理 电话:027-51833411 手机:13237166274

上海源叶生物科技有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:HPLC≥90% 包装信息:20mg,200mg 价格:200.0元 - 1,200.0元
联系方式:
联系人:Alice 电话:021-61845781 手机:13585604150

湖北摆渡化学有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:99% 包装信息:25kg 价格:洽谈
联系方式:
联系人:陈莲芳 电话:027-59265833 手机:18071128683

上海吉至生化科技有限公司

产品介绍:
产品名称:番茄红素 CAS:502-65-8 Cas号:502-65-8 纯度:分析对照品,UV≥98% 包装信息:20mg 价格:洽谈
联系方式:
联系人:刘文军 电话:021-37530392 手机:18911710453/1801801880

湖北帝白化工有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:90 包装信息:洽谈 价格:洽谈
联系方式:
联系人:刘先生 电话:15872383390 手机:15872383390

成都埃法生物科技有限公司

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:HPLC≥95% 包装信息:20mg,5mg 价格:洽谈
联系方式:
联系人:万炯 电话:18030712385 手机:

南京道斯夫生物科技有限公司销售部

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:98% 包装信息:洽谈 价格:洽谈
联系方式:
联系人:林微 电话:025-85562066 手机:13770831292

西安天丰生物科技有限公司销售部

产品介绍:
产品名称:番茄红素 Cas号:502-65-8 纯度:10% 包装信息:1/袋kg 价格:洽谈
联系方式:
联系人:史润利 电话:15802959249 手机:15802959249